He discusses his history and shares a great story from his dad. Bottom line, Dave said he learned early on that he needs to name his price (not just financial) and if it ever gets too expensive than you thought in the beginning - get out of there.
He discusses his friend, the comedian Martin Lawrence, who had a kind of breakdown. He attributes it to the culture of Hollywood. Rather than blaming him, look at the system he is involved in. In an earlier part of the interview he discusses the conflict between art and the corporate machine of the entertainment industry.
Returning to Martin Lawrence and Mariah Carey both of whom had some difficulty and acted in ways that many thought strange, Dave Chappelle says, "The worst thing you can call someone is crazy - it is dismissive. I don't understand this person so they are crazy...these people are not crazy, they are strong people. Maybe the environment is a little sick".
Great commentary and he receives a standing ovation. That is true for our culture too. We should consider that the next time somebody breaks down.